Microvascular density and hypoxia-inducible factor pathway in pancreatic endocrine tumours: negative correlation of microvascular density and VEGF expression with tumour progression

Tumour-associated angiogenesis is partly regulated by the hypoxia-inducible factor (HIF) pathway. Endocrine tumours are highly vascularised and the molecular mechanisms of their angiogenesis are not fully delineated. The aim of this study is to evaluate angiogenesis and expression of HIF-related mol...

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Autors principals: Couvelard, A, O'Toole, D, Turley, H, Leek, R, Sauvanet, A, Degott, C, Ruszniewski, P, Belghiti, J, Harris, A L, Gatter, K, Pezzella, F
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2005
Matèries:
Molecular Diagnostics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361752/
https://ncbi.nlm.nih.gov/pubmed/15558070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602245
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