Cross talk of signals between EGFR and IL-6R through JAK2/STAT3 mediate epithelial–mesenchymal transition in ovarian carcinomas

Epidermal growth factor receptor (EGFR) is overexpressed in ovarian carcinomas, with direct or indirect activation of EGFR able to trigger tumour growth. We demonstrate significant activation of both signal transducer and activator of transcription (STAT)3 and its upstream activator Janus kinase (JA...

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Detaylı Bibliyografya
Asıl Yazarlar: Colomiere, M, Ward, A C, Riley, C, Trenerry, M K, Cameron-Smith, D, Findlay, J, Ackland, L, Ahmed, N
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2009
Konular:
Molecular Diagnostics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634691/
https://ncbi.nlm.nih.gov/pubmed/19088723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604794
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