Reversible monomer-oligomer transition in human prion protein

The structure and the dissociation reaction of oligomers PrP(oligo) from reduced human prion huPrP(C)(23–231) have been studied by (1)H-NMR and tryptophan fluorescence spectroscopy at varying pressure, along with circular dichroism and atomic force microscopy. The (1)H-NMR and fluorescence spectral...

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Detalhes bibliográficos
Main Authors: Sasaki, Ken, Gaikwad, Jyoti, Hashiguchi, Shuhei, Kubota, Toshiya, Sugimura, Kazuhisa, Kremer, Werner, Kalbitzer, Hans Robert, Akasaka, Kazuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2008
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634530/
https://ncbi.nlm.nih.gov/pubmed/19158507
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