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Morphogenic Effects of Ezrin Require a Phosphorylation-Induced Transition from Oligomers to Monomers at the Plasma Membrane

ERM (ezrin, radixin, moesin) proteins act as linkers between the plasma membrane and the actin cytoskeleton. An interaction between their NH(2)- and COOH-terminal domains occurs intramolecularly in closed monomers and intermolecularly in head-to-tail oligomers. In vitro, phosphorylation of a conserv...

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Detalhes bibliográficos
Main Authors: Gautreau, Alexis, Louvard, Daniel, Arpin, Monique
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2185562/
https://ncbi.nlm.nih.gov/pubmed/10893267
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