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Phosphoinositide binding and phosphorylation act sequentially in the activation mechanism of ezrin
Ezrin, a membrane–actin cytoskeleton linker, which participates in epithelial cell morphogenesis, is held inactive in the cytoplasm through an intramolecular interaction. Phosphatidylinositol 4,5-bisphosphate (PIP(2)) binding and the phosphorylation of threonine 567 (T567) are involved in the activa...
Gorde:
| Egile Nagusiak: | , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
The Rockefeller University Press
2004
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172172/ https://ncbi.nlm.nih.gov/pubmed/14993232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200307032 |
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