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Polymorphic Sites Away From the Bw4 Epitope that Affect Interaction of Bw4(+) HLA-B with KIR3DL1
KIR3DL1 is a polymorphic, inhibitory NK-cell receptor specific for the Bw4 epitope carried by subsets of HLA-A and -B allotypes. The Bw4 epitope is determined by the NIALR sequence motif at positions 77, 80, 81, 82 and 83 in the α(1) helix. Mutation, of these positions to the residues present in the...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2634290/ https://ncbi.nlm.nih.gov/pubmed/18941220 |
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