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Regulated Expression of Adenoviral Vectors-Based Gene Therapies: Therapeutic Expression of Toxins and Immune-Modulators

Regulatable promoter systems allow gene expression to be tightly controlled in vivo. This is highly desirable for the development of safe, efficacious adenoviral vectors that can be used to treat human diseases in the clinic. Ideally, regulatable cassettes should have minimal gene expression in the...

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Autores principales: Curtin, James F., Candolfi, Marianela, Puntel, Mariana, Xiong, Weidong, Muhammad, A. K. M., Kroeger, Kurt, Mondkar, Sonali, Liu, Chunyan, Bondale, Niyati, Lowenstein, Pedro R., Castro, Maria G.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633597/
https://ncbi.nlm.nih.gov/pubmed/18470649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-60327-248-3_15
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