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Inhibition of Rho Kinase (ROCK) Leads to Increased Cerebral Blood Flow and Stroke Protection

BACKGROUND AND PURPOSE: Endothelium-derived nitric oxide (NO) plays a pivotal role in vascular protection. The Rho kinase (ROCK) inhibitor, hydroxyfasudil, prevents the downregulation of endothelial NO synthase (eNOS) under hypoxic conditions. However, it is unknown whether inhibition of ROCK can at...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Rikitake, Yoshiyuki, Kim, Hyung-Hwan, Huang, Zhihong, Seto, Minoru, Yano, Kazuo, Asano, Toshio, Moskowitz, Michael A., Liao, James K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2005
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633591/
https://ncbi.nlm.nih.gov/pubmed/16141422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.STR.0000181077.84981.11
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