Increased Leukocyte ROCK Activity in Patients After Acute Ischemic Stroke

BACKGROUND: Rho-kinase (ROCK) is a downstream effector of Rho GTPase that is known to regulate various pathological processes important to the development of ischemic stroke, such as thrombus formation, inflammation, and vasospasm. Inhibition of ROCK leads to decreased infarct size in animal models...

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Autores principales: Feske, Steven K., Sorond, Farzaneh A., Henderson, Galen V., Seto, Minoru, Hitomi, Asako, Kawasaki, Koh, Sasaki, Yasuo, Asano, Toshio, Liao, James K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646801/
https://ncbi.nlm.nih.gov/pubmed/19133241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2008.12.045
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