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Intersubunit allosteric communication mediated by a conserved loop in the MCM helicase

The minichromosome maintenance (MCM) helicase is the presumptive replicative helicase in archaea and eukaryotes. The archaeal homomultimeric MCM has a two-tier structure. One tier contains the AAA+ motor domains of the proteins, and these are the minimal functional helicase domains. The second tier...

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Hlavní autoři: Barry, Elizabeth R., Lovett, Janet E., Costa, Alessandro, Lea, Susan M., Bell, Stephen D.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633543/
https://ncbi.nlm.nih.gov/pubmed/19164574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809192106
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