Risk of Coronary Artery Disease Associated With Polymorphism of the Cytochrome P450 Epoxygenase CYP2J2

BACKGROUND: Cytochrome P450 (CYP) 2J2 is expressed in the vascular endothelium and metabolizes arachidonic acid to biologically active epoxyeicosatrienoic acids (EETs). The EETs are potent endogenous vasodilators and inhibitors of vascular inflammation. However, it is not known whether genetic polym...

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Main Authors: Spiecker, Martin, Darius, Harald, Hankeln, Thomas, Soufi, Muhidien, Sattler, Alexander M., Schaefer, Jürgen R., Node, Koichi, Börgel, Jan, Mügge, Andreas, Lindpaintner, Klaus, Huesing, Anika, Maisch, Bernhard, Zeldin, Darryl C., Liao, James K.
Format: Artigo
Language:Inglês
Published: 2004
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633457/
https://ncbi.nlm.nih.gov/pubmed/15466638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.CIR.0000143832.91812.60
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