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Risk of Coronary Artery Disease Associated With Polymorphism of the Cytochrome P450 Epoxygenase CYP2J2

BACKGROUND: Cytochrome P450 (CYP) 2J2 is expressed in the vascular endothelium and metabolizes arachidonic acid to biologically active epoxyeicosatrienoic acids (EETs). The EETs are potent endogenous vasodilators and inhibitors of vascular inflammation. However, it is not known whether genetic polym...

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Detalhes bibliográficos
Main Authors: Spiecker, Martin, Darius, Harald, Hankeln, Thomas, Soufi, Muhidien, Sattler, Alexander M., Schaefer, Jürgen R., Node, Koichi, Börgel, Jan, Mügge, Andreas, Lindpaintner, Klaus, Huesing, Anika, Maisch, Bernhard, Zeldin, Darryl C., Liao, James K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633457/
https://ncbi.nlm.nih.gov/pubmed/15466638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.CIR.0000143832.91812.60
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