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Production of recombinant AAV vectors encoding insulin-like growth factor I is enhanced by interaction among AAV rep regulatory sequences

BACKGROUND: Adeno-associated virus (AAV) vectors are promising tools for gene therapy. Currently, their potential is limited by difficulties in producing high vector yields with which to generate transgene protein product. AAV vector production depends in part upon the replication (Rep) proteins req...

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Bibliografiska uppgifter
Huvudupphovsmän: Shi, Shuiliang, Mercer, Scott A, Dilley, Robert, Trippel, Stephen B
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2009
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633264/
https://ncbi.nlm.nih.gov/pubmed/19128486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-6-3
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