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Production of recombinant AAV vectors encoding insulin-like growth factor I is enhanced by interaction among AAV rep regulatory sequences
BACKGROUND: Adeno-associated virus (AAV) vectors are promising tools for gene therapy. Currently, their potential is limited by difficulties in producing high vector yields with which to generate transgene protein product. AAV vector production depends in part upon the replication (Rep) proteins req...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2009
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2633264/ https://ncbi.nlm.nih.gov/pubmed/19128486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-6-3 |
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