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Direct quantification of polo-like kinase 1 activity in cells and tissues using a highly sensitive and specific ELISA assay
Polo-like kinase 1 (Plk1) plays a pivotal role in the regulation of cellular proliferation. Plk1 is overexpressed in ≈80% of human tumors of diverse origins, and overexpression of Plk1 promotes neoplastic transformation of human cells. A growing body of evidence suggests that deregulation of Plk1 cl...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2633213/ https://ncbi.nlm.nih.gov/pubmed/19181852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812135106 |
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