Immunobiologically active lipid A analogs synthesized according to a revised structural model of natural lipid A.
Synthetic lipid A analogs which have two amide-bound and two ester-bound (R)-3-hydroxytetradecanoyl groups at the C-2 and -2' and C-3 and -3' positions of beta(1-6)glucosamine disaccharide mono- or diphosphates showed high activities in most in vitro assays, and the lethality of a diphosphate deriva...
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| 出版年: | Infect Immun |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology (ASM)
1984
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC263318/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6735470/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.45.1.293-296.1984 |
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