Immunobiologically active lipid A analogs synthesized according to a revised structural model of natural lipid A.

Synthetic lipid A analogs which have two amide-bound and two ester-bound (R)-3-hydroxytetradecanoyl groups at the C-2 and -2' and C-3 and -3' positions of beta(1-6)glucosamine disaccharide mono- or diphosphates showed high activities in most in vitro assays, and the lethality of a diphosph...

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Detalhes bibliográficos
Main Authors: Kotani, S, Takada, H, Tsujimoto, M, Ogawa, T, Harada, K, Mori, Y, Kawasaki, A, Tanaka, A, Nagao, S, Tanaka, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC263318/
https://ncbi.nlm.nih.gov/pubmed/6735470
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