Immunobiologically active lipid A analogs synthesized according to a revised structural model of natural lipid A.
Synthetic lipid A analogs which have two amide-bound and two ester-bound (R)-3-hydroxytetradecanoyl groups at the C-2 and -2' and C-3 and -3' positions of beta(1-6)glucosamine disaccharide mono- or diphosphates showed high activities in most in vitro assays, and the lethality of a diphosphate deriva...
Guardat en:
| Publicat a: | Infect Immun |
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| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1984
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC263318/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6735470/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.45.1.293-296.1984 |
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