Substituted trans-stilbenes can inhibit or enhance the TPA-induced up-regulation of activator protein-1

BACKGROUND: The activator protein-1 (AP-1) family of transcription factors contributes to regulation of numerous genes involved in proliferation, apoptosis, and tumorigenesis. A wide array of stimuli can activate AP-1, including pro-inflammatory cytokines, growth factors, tumor promoters and stress....

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Detalhes bibliográficos
Main Authors: Deck, Lorraine M, Hunsaker, Lucy A, Gonzales, Amanda M, Orlando, Robert A, Vander Jagt, David L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632638/
https://ncbi.nlm.nih.gov/pubmed/19000313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-8-19
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