Yeast Mph1 helicase dissociates Rad51-made D-loops: implications for crossover control in mitotic recombination

Eukaryotes possess mechanisms to limit crossing over during homologous recombination, thus avoiding possible chromosomal rearrangements. We show here that budding yeast Mph1, an ortholog of human FancM helicase, utilizes its helicase activity to suppress spontaneous unequal sister chromatid exchange...

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Detalhes bibliográficos
Main Authors: Prakash, Rohit, Satory, Dominik, Dray, Eloïse, Papusha, Almas, Scheller, Jürgen, Kramer, Wilfried, Krejci, Lumir, Klein, Hannah, Haber, James E., Sung, Patrick, Ira, Grzegorz
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632165/
https://ncbi.nlm.nih.gov/pubmed/19136626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1737809
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