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Enhanced Secretion of Biologically Active Murine Interleukin-12 by Lactococcus lactis
The novel signal peptide SLPmod was used for the secretion of murine interleukin-12 (mIL-12) by Lactococcus lactis. A >4-fold increase in secretion was observed when SLPmod was used instead of the Usp45-derived secretion signal. Oral delivery of this cytokine using the autoinducible host L. lacti...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2632150/ https://ncbi.nlm.nih.gov/pubmed/19060166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01728-08 |
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