Leptospira interrogans Induces Apoptosis in Macrophages via Caspase-8- and Caspase-3-Dependent Pathways

Apoptosis of host cells plays an important role in modulating the pathogenesis of many infectious diseases. It has been reported that Leptospira interrogans, the causal agent of leptospirosis, induces apoptosis in macrophages and hepatocytes. However, the molecular mechanisms responsible for host ce...

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Detalhes bibliográficos
Main Authors: Jin, Dandan, Ojcius, David M., Sun, Dexter, Dong, Haiyan, Luo, Yihui, Mao, Yafei, Yan, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632035/
https://ncbi.nlm.nih.gov/pubmed/19029301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00914-08
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