Leptospira interrogans Induces Apoptosis in Macrophages via Caspase-8- and Caspase-3-Dependent Pathways

Apoptosis of host cells plays an important role in modulating the pathogenesis of many infectious diseases. It has been reported that Leptospira interrogans, the causal agent of leptospirosis, induces apoptosis in macrophages and hepatocytes. However, the molecular mechanisms responsible for host ce...

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Bibliographische Detailangaben
Hauptverfasser: Jin, Dandan, Ojcius, David M., Sun, Dexter, Dong, Haiyan, Luo, Yihui, Mao, Yafei, Yan, Jie
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2009
Schlagworte:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632035/
https://ncbi.nlm.nih.gov/pubmed/19029301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00914-08
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