Leptospira interrogans Induces Apoptosis in Macrophages via Caspase-8- and Caspase-3-Dependent Pathways

Apoptosis of host cells plays an important role in modulating the pathogenesis of many infectious diseases. It has been reported that Leptospira interrogans, the causal agent of leptospirosis, induces apoptosis in macrophages and hepatocytes. However, the molecular mechanisms responsible for host ce...

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Hlavní autoři: Jin, Dandan, Ojcius, David M., Sun, Dexter, Dong, Haiyan, Luo, Yihui, Mao, Yafei, Yan, Jie
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632035/
https://ncbi.nlm.nih.gov/pubmed/19029301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00914-08
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