Differential Roles of Blocking Ions in KirBac1.1 Tetramer Stability

Potassium channels are tetrameric proteins that mediate K(+)-selective transmembrane diffusion. For KcsA, tetramer stability depends on interactions between permeant ions and the channel pore. We have examined the role of pore blockers on the tetramer stability of KirBac1.1. In 150 mm KCl, purified...

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Bibliographic Details
Main Authors: Wang, Shizhen, Alimi, Yewande, Tong, Ailing, Nichols, Colin G., Enkvetchakul, Decha
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Protein Structure and Folding
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631979/
https://ncbi.nlm.nih.gov/pubmed/19033439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807474200
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