Differential Roles of Blocking Ions in KirBac1.1 Tetramer Stability

Potassium channels are tetrameric proteins that mediate K(+)-selective transmembrane diffusion. For KcsA, tetramer stability depends on interactions between permeant ions and the channel pore. We have examined the role of pore blockers on the tetramer stability of KirBac1.1. In 150 mm KCl, purified...

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Bibliografiske detaljer
Main Authors: Wang, Shizhen, Alimi, Yewande, Tong, Ailing, Nichols, Colin G., Enkvetchakul, Decha
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Protein Structure and Folding
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631979/
https://ncbi.nlm.nih.gov/pubmed/19033439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807474200
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