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Molecular Dynamics Simulations of KirBac1.1 Mutants Reveal Global Gating Changes of Kir Channels

[Image: see text] Prokaryotic inwardly rectifying (KirBac) potassium channels are homologous to mammalian Kir channels. Their activity is controlled by dynamical conformational changes that regulate ion flow through a central pore. Understanding the dynamical rearrangements of Kir channels during ga...

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Bibliografiske detaljer
Udgivet i:J Chem Inf Model
Main Authors: Linder, Tobias, Wang, Shizhen, Zangerl-Plessl, Eva-Maria, Nichols, Colin G., Stary-Weinzinger, Anna
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2015
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415035/
https://ncbi.nlm.nih.gov/pubmed/25794351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.5b00010
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