Functional Complementation and Genetic Deletion Studies of KirBac Channels: ACTIVATORY MUTATIONS HIGHLIGHT GATING-SENSITIVE DOMAINS

The superfamily of prokaryotic inwardly rectifying (KirBac) potassium channels is homologous to mammalian Kir channels. However, relatively little is known about their regulation or about their physiological role in vivo. In this study, we have used random mutagenesis and genetic complementation in...

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Autors principals: Paynter, Jennifer J., Andres-Enguix, Isabelle, Fowler, Philip W., Tottey, Stephen, Cheng, Wayland, Enkvetchakul, Decha, Bavro, Vassiliy N., Kusakabe, Yoshio, Sansom, Mark S. P., Robinson, Nigel J., Nichols, Colin G., Tucker, Stephen J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
Matèries:
Membrane Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003375/
https://ncbi.nlm.nih.gov/pubmed/20876570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.175687
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