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Sox9 Inhibits Wnt Signaling by Promoting β-Catenin Phosphorylation in the Nucleus
Chondrocyte fate determination and maintenance requires Sox9, an intrinsic transcription factor, but is inhibited by Wnt/β-catenin signaling activated by extrinsic Wnt ligands. Here we explored the underlying molecular mechanism by which Sox9 antagonizes the Wnt/β-catenin signaling in chondrocyte di...
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| Asıl Yazarlar: | , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Biochemistry and Molecular Biology
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2631972/ https://ncbi.nlm.nih.gov/pubmed/19047045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808048200 |
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