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Cyclic Ketimines as Superior Electrophiles for NHC-Catalyzed Homoenolate Additions with Broad Scope and Low Catalyst Loadings

[Image: see text] Cyclic sulfonyl imines derived from ketones were identified as stable and readily prepared compounds that serve as superior electrophiles for N-heterocyclic carbene (NHC)-catalyzed annulations with α,β-unsaturated aldehydes to afford highly substituted γ-lactams. Their superior rea...

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Detalhes bibliográficos
Main Authors: Rommel, Michael, Fukuzumi, Takeo, Bode, Jeffrey W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631935/
https://ncbi.nlm.nih.gov/pubmed/19053399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja807937m
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