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Emerging mechanisms of fluoroquinolone resistance.
Broad use of fluoroquinolones has been followed by emergence of resistance, which has been due mainly to chromosomal mutations in genes encoding the subunits of the drugs' target enzymes, DNA gyrase and topoisomerase IV, and in genes that affect the expression of diffusion channels in the outer...
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Centers for Disease Control and Prevention
2001
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2631735/ https://ncbi.nlm.nih.gov/pubmed/11294736 |
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