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Generation of potent neutralizing human monoclonal antibodies against cytomegalovirus infection from immune B cells

BACKGROUND: Human monoclonal antibodies (mAbs) generated as a result of the immune response are likely to be the most effective therapeutic antibodies, particularly in the case of infectious diseases against which the immune response is protective. Human cytomegalovirus (HCMV) is an ubiquitous oppor...

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Détails bibliographiques
Auteurs principaux: Funaro, Ada, Gribaudo, Giorgio, Luganini, Anna, Ortolan, Erika, Lo Buono, Nicola, Vicenzi, Elisa, Cassetta, Luca, Landolfo, Santo, Buick, Richard, Falciola, Luca, Murphy, Marianne, Garotta, Gianni, Malavasi, Fabio
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631500/
https://ncbi.nlm.nih.gov/pubmed/19014469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-8-85
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