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Sp1-mediated TRAIL induction in chemo-sensitization
The regulation of TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) in cancer chemotherapy is not fully understood. Here, we show that the HDACIs (inhibitors of histone deacetylases) induce TRAIL in human breast cancer cells. Induction of TRAIL by the HDACI MS275 can be enhanced by adr...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2631399/ https://ncbi.nlm.nih.gov/pubmed/18701496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-0657 |
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