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COX2 in CNS neural cells mediates mechanical inflammatory pain hypersensitivity in mice

A cardinal feature of peripheral inflammation is pain. The most common way of managing inflammatory pain is to use nonsteroidal antiinflammatory agents (NSAIDs) that reduce prostanoid production, for example, selective inhibitors of COX2. Prostaglandins produced after induction of COX2 in immune cel...

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Bibliografische gegevens
Hoofdauteurs: Vardeh, Daniel, Wang, Dairong, Costigan, Michael, Lazarus, Michael, Saper, Clifford B., Woolf, Clifford J., FitzGerald, Garret A., Samad, Tarek A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631301/
https://ncbi.nlm.nih.gov/pubmed/19127021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI37098
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