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Periganglionic inflammation elicits a distally radiating pain hypersensitivity by promoting COX-2 induction in the dorsal root ganglion

We have developed a model in which inflammation contiguous to and within a dorsal root ganglion (DRG) was generated by local application of complete Freund’s adjuvant (CFA) to the L4 lumbar spinal nerve as it exits from the intervertebral foramen. The periganglionic inflammation (PGI) elicited a mar...

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Detalhes bibliográficos
Main Authors: Amaya, Fumimasa, Samad, Tarek A., Barrett, Lee, Broom, Daniel C., Woolf, Clifford J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755568/
https://ncbi.nlm.nih.gov/pubmed/19135800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2008.11.013
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