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Estimating Protein-Ligand Binding Affinity using High-Throughput Screening by NMR
Many of today’s drug discovery programs utilize high-throughput screening methods that rely on quick evaluations of protein activity to rank potential chemical leads. By monitoring biologically relevant protein-ligand interactions, NMR can provide a means to validate these discovery leads and to opt...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2631241/ https://ncbi.nlm.nih.gov/pubmed/18831571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cc800122m |
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