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Statistical Removal of Background Signals from High-throughput (1)H NMR Line-broadening Ligand-affinity Screens
NMR ligand-affinity screens are vital to drug discovery, are routinely used to screen fragment-based libraries, and used to verify chemical leads from high-throughput assays and virtual screens. NMR ligand-affinity screens are also a highly informative first step towards identifying functional epito...
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Publicado no: | J Biomol NMR |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4577452/ https://ncbi.nlm.nih.gov/pubmed/26156049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-015-9962-3 |
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