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Exploring structural variability in X-ray crystallographic models using protein local optimization by torsion-angle sampling

Modeling structural variability is critical for understanding protein function and for modeling reliable targets for in silico docking experiments. Because of the time-intensive nature of manual X-ray crystallographic refinement, automated refinement methods that thoroughly explore conformational sp...

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Bibliografische gegevens
Hoofdauteurs: Knight, Jennifer L., Zhou, Zhiyong, Gallicchio, Emilio, Himmel, Daniel M., Friesner, Richard A., Arnold, Eddy, Levy, Ronald M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: International Union of Crystallography 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2631124/
https://ncbi.nlm.nih.gov/pubmed/18391405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S090744490800070X
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