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In silico vaccine design based on molecular simulations of rhinovirus chimeras presenting HIV-1 gp41 epitopes

A cluster of promising epitopes for the development of HIV vaccines is located in the membrane-proximal external region (MPER) of the gp41 subunit of the HIV envelope spike structure. The crystal structure of the peptide corresponding to the so-called ELDKWA epitope (HIV-1 HxB2 gp41 residues 662–668...

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Detalhes bibliográficos
Main Authors: Lapelosa, Mauro, Gallicchio, Emilio, Arnold, Gail Ferstandig, Arnold, Eddy, Levy, Ronald M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649764/
https://ncbi.nlm.nih.gov/pubmed/19026659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.10.089
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