Single-chain Fv phage display propensity exhibits strong positive correlation with overall expression levels

BACKGROUND: Single chain Fvs (scFvs) are widely applied in research, diagnostics and therapeutic settings. Display and selection from combinatorial libraries is the main route to their discovery and many factors influence the success of this process. They exhibit low thermodynamic stability, resulti...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Scott, Nathan, Reynolds, Catherine B, Wright, Michael J, Qazi, Omar, Fairweather, Neil, Deonarain, Mahendra P
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630973/
https://ncbi.nlm.nih.gov/pubmed/19113995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-8-97
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky