Mice Lacking β-Adrenergic Receptors Have Increased Bone Mass but Are Not Protected from Deleterious Skeletal Effects of Ovariectomy

Activation of β2-adrenergic receptors inhibits osteoblastic bone formation and enhances osteoclastic bone resorption. Whether β-blockers inhibit ovariectomy-induced bone loss and decrease fracture risk remains controversial. To further explore the role of β-adrenergic signaling in skeletal acquisiti...

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Hlavní autoři: Bouxsein, M. L., Devlin, M. J., Glatt, V., Dhillon, H., Pierroz, D. D., Ferrari, S. L.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Endocrine Society 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630907/
https://ncbi.nlm.nih.gov/pubmed/18801900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-0843
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