β-Arrestin2 Regulates the Differential Response of Cortical and Trabecular Bone to Intermittent PTH in Female Mice

Cytoplasmic arrestins regulate PTH signaling in vitro. We show that female β-arrestin2(-/-) mice have decreased bone mass and altered bone architecture. The effects of intermittent PTH administration on bone microarchitecture differed in β-arrestin2(-/-) and wildtype mice. These data indicate that a...

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Bibliografiske detaljer
Main Authors: Bouxsein, Mary L, Pierroz, Dominique D, Glatt, Vaida, Goddard, Deborah S, Cavat, Fanny, Rizzoli, René, Ferrari, Serge L
Format: Artigo
Sprog:Inglês
Udgivet: 2004
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1586119/
https://ncbi.nlm.nih.gov/pubmed/15765183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/JBMR.041204
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