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Abnormal proteins can form aggresome in yeast: aggresome-targeting signals and components of the machinery
In mammalian cells, abnormal proteins that escape proteasome-dependent degradation form small aggregates that can be transported into a centrosome-associated structure, called an aggresome. Here we demonstrate that in yeast a single aggregate formed by the huntingtin exon 1 with an expanded polyglut...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Federation of American Societies for Experimental Biology
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2630789/ https://ncbi.nlm.nih.gov/pubmed/18854435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-117614 |
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