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Dynamic Compartmentalization of Base Excision Repair Proteins in Response to Nuclear and Mitochondrial Oxidative Stress

DNAs harbored in both nuclei and mitochondria of eukaryotic cells are subject to continuous oxidative damage resulting from normal metabolic activities or environmental insults. Oxidative DNA damage is primarily reversed by the base excision repair (BER) pathway, initiated by N-glycosylase apurinic/...

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Библиографические подробности
Главные авторы: Griffiths, Lyra M., Swartzlander, Dan, Meadows, Kellen L., Wilkinson, Keith D., Corbett, Anita H., Doetsch, Paul W.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630693/
https://ncbi.nlm.nih.gov/pubmed/19029246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01357-08
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