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Unusual Telomeric DNAs in Human Telomerase-Negative Immortalized Cells

A significant fraction of human cancer cells and immortalized cells maintain telomeres in a telomerase-independent manner called alternative lengthening of telomeres (ALT). It has been suggested that ALT involves homologous recombination that is expected to generate unique intermediate DNAs. However...

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Autors principals: Nabetani, Akira, Ishikawa, Fuyuki
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630689/
https://ncbi.nlm.nih.gov/pubmed/19015236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00603-08
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