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Phylogenetic Conservation and Homology Modeling Help Reveal a Novel Domain within the Budding Yeast Heterochromatin Protein Sir1

The yeast Sir1 protein's ability to bind and silence the cryptic mating-type locus HMRa requires a protein-protein interaction between Sir1 and the origin recognition complex (ORC). A domain within the C-terminal half of Sir1, the Sir1 ORC interaction region (Sir1OIR), and the conserved bromo-a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hou, Zhonggang, Danzer, John R., Mendoza, Liza, Bose, Melissa E., Müller, Ulrika, Williams, Barry, Fox, Catherine A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630688/
https://ncbi.nlm.nih.gov/pubmed/19029247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00202-08
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