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Differential DNA affinity specifies roles for the origin recognition complex in budding yeast heterochromatin

The origin recognition complex (ORC) marks chromosomal positions as replication origins and is essential for replication initiation. At a few loci, the ORC functions in heterochromatin formation. We show that the ORC's two roles at the heterochromatic HMRa locus in Saccharomyces cerevisiae were...

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Detalhes bibliográficos
Main Authors: Palacios DeBeer, Madeleine A., Müller, Ulrika, Fox, Catherine A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC196224/
https://ncbi.nlm.nih.gov/pubmed/12897051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1096703
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