Differential DNA affinity specifies roles for the origin recognition complex in budding yeast heterochromatin

The origin recognition complex (ORC) marks chromosomal positions as replication origins and is essential for replication initiation. At a few loci, the ORC functions in heterochromatin formation. We show that the ORC's two roles at the heterochromatic HMRa locus in Saccharomyces cerevisiae were...

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Bibliographic Details
Main Authors: Palacios DeBeer, Madeleine A., Müller, Ulrika, Fox, Catherine A.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2003
Subjects:
Research Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC196224/
https://ncbi.nlm.nih.gov/pubmed/12897051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1096703
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