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Differential DNA affinity specifies roles for the origin recognition complex in budding yeast heterochromatin
The origin recognition complex (ORC) marks chromosomal positions as replication origins and is essential for replication initiation. At a few loci, the ORC functions in heterochromatin formation. We show that the ORC's two roles at the heterochromatic HMRa locus in Saccharomyces cerevisiae were...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC196224/ https://ncbi.nlm.nih.gov/pubmed/12897051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1096703 |
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