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Lysine-Independent Turnover of Cyclin G1 Can Be Stabilized by B′α Subunits of Protein Phosphatase 2A

Although the cyclin G1 gene is known to be regulated at the transcriptional level by p53, less is understood about the turnover of its protein product. We found that ectopically and endogenously expressed cyclin G1 protein is highly unstable and is degraded by a proteasome-mediated pathway. The N-te...

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Библиографические подробности
Главные авторы: Li, Hongyun, Okamoto, Koji, Peart, Melissa J., Prives, Carol
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630686/
https://ncbi.nlm.nih.gov/pubmed/18981217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00907-08
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