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Voriconazole Increases while Itraconazole Decreases Plasma Meloxicam Concentrations
This study investigated the effect of voriconazole, an inhibitor of cytochrome P450 2C9 (CYP2C9) and CYP3A4, and itraconazole, an inhibitor of CYP3A4, on the pharmacokinetics and pharmacodynamics of meloxicam. Twelve healthy volunteers in a crossover study ingested 15 mg of meloxicam without pretrea...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology (ASM)
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2630625/ https://ncbi.nlm.nih.gov/pubmed/19015346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00530-08 |
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