Effect of voriconazole on the pharmacokinetics and pharmacodynamics of zolpidem in healthy subjects

AIMS: To assess the effect of voriconazole on the pharmacokinetics and pharmacodynamics of zolpidem. METHODS: In a randomized cross-over study with two phases, 10 healthy subjects ingested 10 mg of zolpidem with or without oral voriconazole pretreatment. The concentrations of zolpidem were measured...

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Detalhes bibliográficos
Main Authors: Saari, Teijo I, Laine, Kari, Leino, Kari, Valtonen, Mika, Neuvonen, Pertti J, Olkkola, Klaus T
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2007
Assuntos:
Short Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000716/
https://ncbi.nlm.nih.gov/pubmed/16822278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2006.02707.x
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