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Reassessment of Recommended Imipenem Doses in Febrile Neutropenic Patients with Hematological Malignancies
Imipenem plasma concentrations were analyzed in 57 febrile neutropenic patients using the NONMEM program. The recommended 2-g/day regimen achieved coverage of the most common bacteria (MIC(90) = 1 mg/liter) during the whole dosing interval in only 53% of patients. This goal was achieved in 90% of pa...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology (ASM)
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2630622/ https://ncbi.nlm.nih.gov/pubmed/19047655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00891-08 |
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