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Discovery of a Small-Molecule Inhibitor of β-1,6-Glucan Synthesis

It is possible that antifungal drugs with novel modes of action will provide favorable options to treat fungal infections. In the course of our screening for antifungal compounds acting on the cell wall, a pyridobenzimidazole derivative with unique activities, named D75-4590, was discovered. During...

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主要な著者: Kitamura, Akihiro, Someya, Kazuhiko, Hata, Masato, Nakajima, Ryohei, Takemura, Makoto
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630612/
https://ncbi.nlm.nih.gov/pubmed/19015325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00844-08
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